Table V.
Areas of significant association between diffusion tensor, white matter hyper‐intensities measurements and executive dysfunctions
VF | WCST‐c | WCST‐p | TMT‐A | TMT‐B | FBI‐n | FBI‐d | |
---|---|---|---|---|---|---|---|
Diffusion tensor measurements in periventricular white matter | |||||||
Frontal R/L | */− | *†/* | *†/*† | −/* | */* | −/* | −/− |
Parietal R/L | */* | −/− | *†/*† | */* | −/− | −/− | −/− |
Diffusion tensor measurements in subcortical white matter | |||||||
Frontal R/L | −/− | */− | −/− | −/− | −/− | −/− | −/− |
Parietal R/L | −/− | −/− | −/− | −/− | −/− | −/− | −/− |
Temporal R/L | −/‡ | −/− | −/− | −/− | −/− | −/− | −/− |
Diffusion tensor measurements in corpus callosum | |||||||
Genu | −/* | −/− | −/− | −/− | −/− | −/− | −/− |
Splenium | −/− | −/− | −/− | −/− | −/− | −/− | −/− |
White matter hyper‐intensities | |||||||
Frontal R/L | −/− | −/− | −/− | −/− | −/− | −/− | −/− |
Parietal R/L | −/− | −/− | −/− | −/− | −/− | −/− | −/− |
Temporal R/L | −/− | −/− | −/− | −/− | −/− | −/− | −/− |
For all subjects; †For MCI; ‡For early AD, P < 0.01, Pearson correlation analysis; VF, verbal fluency test; WCST, Wisconsin card sorting test; c, number of completed categories; p, number of perseverative errors; TMT, trail making; A, part A; B, part B; FBI, frontal behavioral inventory; n, negative behavioral score; d, disinhibition score.