Table III.

Location and LPM measures of ‘progressive’ T2 lesions

Projection‐and commissural fibres	Association fibres	Hemi‐sphere	MNI coordinates (x y z)	Clustersize (voxels)	P uncorrected	P corrected
Callosal body and Optic radiation	Anterior thalamic radiation; Forceps major; Cingulum (hippocampus)	Right	22 −51 26	2535	<0.001	<0.01
	ILF Inferior occipitofrontal fasciculus	Left	−35 −43 −9	227	<0.01	0.079
	Forceps major Cingulum (hippocampus)	Left	−22 −55 19	52	<0.01	0.079
Callosal body	n.l.f	Right	18 −16 31	305	<0.001	0.056
	Superior occipitofrontal fasciculus	Left	−27 −33 22	73	<0.01	0.077
	n.l.f	Left	−17 −33 26	61	<0.01	0.094
	n.l.f	Right	18 −29 34	53	<0.01	0.087
Corticospinal tract	SLF	Left	−31 −17 26	598	<0.01	0.058
	SLF	Right	31 −11 19	67	<0.01	0.081
	SLF	Right	31 −5 26	59	<0.01	0.094
	Superior occipitofrontal fasciculus; Anterior thalamic radiation	Right	22 11 21	389	<0.01	0.056
	SLF	Left	−25 9 19	155	<0.001	0.063
ITG, optic radiation	ILF, SLF	Left	−44 −34 −15	61	<0.01	0.089

Projection and commissural fibres refer to the anatomy toolbox of SPM5, Wellcome Department of Imaging Neurosciences, University College London, [http://www.fil.ion.ucl.ac.uk/spm]. Association fibres refer to the Jülich Histological Atlas (JHU) and the JHU WM tractography atlas, implemented in FMRIB's Software Library (FSL). ITG, inferior temporal gyrus; ILF, inferior longitudinal fasciculus; SLF, superior longitudinal fasciculus; n.l.f, no label found.