Table II.
Diffusion‐tensor MRI‐derived metrics of the corpus callosum from benign MS patients with and without cognitive impairment
| CI BMS | CP BMS | P | |
|---|---|---|---|
| Average NAWM MD (SD) | 0.82 (0.05) | 0.78 (0.04) | 0.02 |
| Average NAWM FA (SD) | 0.44 (0.06) | 0.47 (0.03) | 0.16 |
| Mean JD (SD) | 0.89 (0.03) | 0.90 (0.04) | 0.45 |
| Average lesion FA | 0.34 (0.04) | 0.35 (0.06) | 0.64 |
| Average lesion MD | 1.25 (0.13) | 1.21 (0.14) | 0.38 |
Average MD of the diffusivity histogram is expressed in units of mm2/s × 10−3, FA is dimensionless index. CI, cognitively impaired; BMS, benign multiple sclerosis; CP, cognitively preserved; NAWM, normal‐appearing white matter; MD, mean diffusivity; SD, standard deviation; FA, fractional anisotropy; JD, Jacobian determinant.