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. 2008 Dec 31;30(8):2617–2627. doi: 10.1002/hbm.20693

Figure 2.

Figure 2

Comparisons between healthy subjects and depressed patients concerning judgment of self‐relatedness and PV (PJ > PV). SPM images show statistical parametric (T) maps for comparisons between healthy subjects and patients with MDD, overlaid on a single subject's normalized brain in the MNI stereotactic space (P < 0.001; uncorrected; k > 5). The saggital view represents the left hemisphere in the upper panel and the right hemisphere in the lower panel. Bar diagrams show % signal changes in judgment of self‐relatedness (PJ) and passive viewing (PV) in healthy controls and patients with MDD. Time curves show % signal changes in judgment of self‐relatedness in healthy controls and patients with MDD. Time curves and bar diagrams represent the % signal changes in the precuneus (−4, −72, 38), DMPFC (−8, 36, 12), DMT (12, −14, 14), and SACC (12, 30, 28) for healthy controls and MDD. PJ, picture judgment; PV, picture viewing; DMPFC, dorsomedial prefrontal cortex; DMT, dorsomedial thalamus; SACC, supragenual anterior cingulate cortex; MDD, major depressive disorder. [Color figure can be viewed in the online issue, which is available at www.interscience.wiley.com.]