Figure 4.

Correlation of depression symptom severity (BDI) with BOLD signals obtained in the contrast PJ > PV in patients with MDD. The SPM image shows a statistical parametric (T) map for the comparison between healthy subjects and patients with MDD, overlaid on a single subject's normalized brain in the MNI stereotactic space (P < 0.001; uncorrected; k > 5) during PJ > PV. The saggital view represents the left hemisphere. The scatter plot shows BDI subscore ratings for negative self‐concept on x‐axis and % signal change in DMPFC (−8, 36, 12) during PJ > PV on y‐axis. The scatter plot is presented for depressed subjects (**P < 0.01). DMPFC, dorsomedial prefrontal cortex; BDI, Beck Depression Inventory, MDD, major depressive disorder. [Color figure can be viewed in the online issue, which is available at www.interscience.wiley.com.]