Table I.
Brain areas that showed significantly reduced gray matter concentration/volume in MTLE/HS patients compared to controls
| Anatomical location | MNI coordinates (x, y, z) | Cluster size (number of voxels) | Z‐score |
|---|---|---|---|
| GMC | |||
| Ipsi hippocampus and parahippocampal gyrus | −31, −9, −22 | 1229 | 5.48 |
| GMV | |||
| Ipsi hippocampus and parahippocampal gyrus | −25, −36, −4 | 9160 | 5.66 |
| Ipsi cerebellum | −14, −32, −20 | 843 | 4.43 |
| Ipsi thalamus | −7, −25, 13 | 785 | 4.37 |
| Ipsi caudate | −11, 11, 6 | 276 | 4.06 |
| Ipsi posterior cingulate/BA 31/ | −13, −24, 42 | 276 | 3.99 |
| Ipsi superior temporal gyrus /BA 22/ | −58, −55, 13 | 111 | 3.65 |
| Ipsi inferior temporal gyrus/BA 37/ | −59, −52, −11 | 115 | 3.64 |
| Contra anterior cingulate/BA 32/ | 5, 20, 39 | 202 | 3.61 |
Voxel size 1 × 1 × 1 mm. Ipsi, ipsilateral; contra, contralateral to the side of HS. Height threshold: P < 0.05 FDR corrected; minimum cluster size = 100 adjacent voxels.