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. 2007 Oct 19;29(12):1327–1342. doi: 10.1002/hbm.20470

Figure 2.

Figure 2

Regions of cerebral activations related to the hyperalgesia conditions: (A) heat hyperalgesia and (B) mechanical hyperalgesia. Group activations were registered onto a Talairach‐transformed brain in axial view, thresholded at T > 4, P < 0.0005, uncorrected for multiple comparisons and a cluster threshold of 300 voxels. For statistical comparison T‐statistic contrast maps comparing (C) heat hyperalgesia vs. heat pain and (D) mechanical hyperalgesia vs. mechanical pain are depicted. The group statistic contrast maps are registered onto a Talairach‐transformed brain, thresholded at T > 2, P < 0.05 uncorrected for multiple comparisons and a cluster threshold of 300 voxels. Activations seen in the left hemisphere are contralateral to the stimulation side. The Talairachcoordinates, T‐scores, Bonferroni‐corrected P values and cluster sizes are depicted in Table I. Abbreviations: ACC, anterior cingulate cortex; PCC, posterior cingulate cortex, TH, thalamus; SFC, superior frontal cortex; MFC, middle frontal cortex; IFC, inferior frontal cortex, S1, primary somatosensory cortex; S2, secondary somatosensory cortex; PA, parietal association cortex.