Figure 6.

Common activation patterns: Conjunction analysis reveals areas with (A) similar effect of sensitization regardless of modality and (B) similar effect of modality regardless of sensitization state. Areas that are coded red/yellow in (A) showed a similar effect of sensitization during heat and mechanical stimuli. Areas that are coded in red/yellow in (B) showed a similar response to heat stimuli in the nonsensitized and the sensitized area. Areas that are coded in blue/green in (B) showed a similar response to mechanical stimuli in the nonsensitized and the sensitized area. The group statistic contrast maps are registered onto a Talairachtransformed brain, thresholded at T > 2, P < 0.05 uncorrected for multiple comparisons and a cluster threshold of 300 voxels. Activations seen in the left hemisphere are contralateral to the stimulation side. The Talairach‐coordinates and cluster sizes are depicted in Table I. Abbreviations: ACC, anterior cingulate cortex; PCC, posterior cingulate cortex; TH, thalamus; SFC, superior frontal cortex; MFC, middle frontal cortex; IFC, inferior frontal cortex; S1, primary somatosensory cortex; S2, secondary somatosensory cortex; PA, parietal association cortex. The mean parameter estimates (beta values) for each condition in (C) areas with a common effect of sensitization and (D) areas with a common effect of modality are shown. Error bars indicate SEM.