Figure 4.

Select examples of diverse product transformations of enantio- and diastereoselective iridium-catalyzed allylic alkylation products 51^a

^aConditions: (a) pyrrolidine, AcOH, t-BuOMe, reflux, 95% yield. (b) Co₂(CO)₈, CH₂Cl₂, then Me₃NO×2H₂O, >20:1 dr, 99% yield. (c) HG-II (10 mol %), CH₂Cl₂, 40 °C, 96% yield. (d) i) allylmagnesium chloride, THF, −78 °C, 71% yield, ii) HG-II, CH₂Cl₂, 81% yield, iii) K₂OsO₄, NMO, THF/H₂O, 59% yield. (e) Me₃S(O)I, NaH, DMSO, 82% yield. (f) K₂OsO₄, NMO, THF/H₂O, 65% yield.