Figure 1.

How developmental trajectories can go awry. In all examples hypothetical data representing the change in cortical thickness of a cerebral point is given. (A) The pathological trajectory has the same form as the typical trajectory but is displaced rightward along the age axis and so key characteristics such as the age of peak thickness, shown in the bold arrows, is attained later. (B) The pathological trajectory has the same form, but changes at a higher velocity. (C) The pathological trajectory loses the form or shape of a typical trajectory.