Table II.

Mean diffusivity and fractional anisotropy values of the assessed white matter tracts in healthy controls, patients with amnestic mild cognitive impairment, and patients with Alzheimer's disease

	HC	aMCI	AD	P
Fornix
MD	0.87 (0.07)	0.93 (0.06)	0.93 (0.10)	0.06
FA	0.42 (0.03)	0.41 (0.03)	0.38 (0.03)*	0.05
Cingulum
MD	0.74 (0.03)	0.76 (0.03)	0.78 (0.03)*	0.02
FA	0.56 (0.04)	0.55 (0.04)	0.53 (0.05)	0.55
Uncinate
MD	0.81 (0.04)	0.84 (0.05)	0.86 (0.04)*	0.03
FA	0.40 (0.04)	0.41 (0.03)	0.39 (0.02)	0.45
Inferior fronto‐occipital
MD	0.81 (0.04)	0.82 (0.04)	0.84 (0.04)	0.09
FA	0.52 (0.04)	0.54 (0.04)	0.51 (0.03)	0.12
ILF
MD	0.80 (0.06)	0.84 (0.05)	0.88 (0.05)*	0.002
FA	0.46 (0.03)	0.46 (0.02)	0.45 (0.03)	0.70
SLF
MD	0.74 (0.03)	0.76 (0.03)	0.78 (0.04)*	0.02
FA	0.48 (0.04)	0.48 (0.03)	0.48 (0.03)	0.73
Corpus callosum
MD	0.76 (0.03)	0.78 (0.04)	0.81 (0.05)*	0.02
FA	0.60 (0.04)	0.61 (0.03)	0.59 (0.04)	0.82

Abbreviations: HC, healthy controls; aMCI, amnestic mild cognitive impairment; AD, Alzheimer's disease; GLM, general linear model; MD, mean diffusivity; FA, fractional anisotropy; ILF, inferior longitudinal fasciculus; SLF, superior longitudinal fasciculus.

MD values are ×10⁻³ mm² s⁻¹.

Values are mean (standard deviation).

^*Significantly different (P < 0.05) between AD and HC in Bonferroni‐corrected post‐hoc analysis.