Table I.
Familial cortical myoclonic tremor with epilepsy patients
| Patient | Age (in years) | Gender | Symptoms | AED | Clinical electrophysiology | |||||
|---|---|---|---|---|---|---|---|---|---|---|
| Tremora | GTCSa | seiz fra | EEG changes | g‐SEP | C‐reflex | EEG‐EMG coherence | ||||
| FCMTE 1b | 19 | F | 12 | − | − | − | − | − | + | nd |
| FCMTE 2 | 31 | F | 20 | − | − | − | − | + | + | + |
| FCMTE 3 | 33 | M | 22 | − | − | − | − | + | + | + |
| FCMTE 4 | 43 | M | 19 | 20 | + | PhB, VPA, CBZ | nd | nd | nd | + |
| FCMTE 5 | 45 | F | 38 | 42 | ± | VPA, CZP | not specific | + | + | + |
| FCMTE 6 | 46 | M | 12 | 31 | ± | VPA, CZP | nd | nd | nd | + |
| FCMTE 7 | 56 | M | 30 | 43 | + | OCB, CZP | spike‐wave | − | + | + |
| FCMTE 8 | 59 | M | 45 | 52 | ± | VPA, CBZ | spike‐wave | + | − | + |
AED: anti‐epileptic drug; C‐reflex: cortical reflex, long latency reflex; CBZ: clobazam; CZP: clonazepam; EEG: electroencephalogram; EMG: electromyogram; F: female; FCMTE: familial cortical myoclonic tremor with epilepsy; g‐SEP: giant sensory evoked potential; GTCS: generalized tonic clonic seizure; M: male; nd: not done; OCB: oxcarbamazepine; PhB: phenobarbital; seiz fr: seizure frequency; VPA: valproic acid; −: negative/none; ±: good control with AEDs; +: present/few seizures per year on AEDs.
a
Age at onset.
b
Left handed.