. Author manuscript; available in PMC: 2019 Nov 21.

Published in final edited form as: J Trauma Acute Care Surg. 2019 Apr;86(4):679–685. doi: 10.1097/TA.0000000000002165

TABLE 3.

Conventional Coagulation and Blood Product Transfusion Characteristics of ROTEM Fibrinolysis Phenotypes

Variable	SD (CLI60 > 98%)	PHY (CLI60 > 82–97.9%)	HYPER (CLI60 < 82%)	Kruskal-Wallis p
INR	1.26(1.08–1.39)^,^*	1.08(1.02–1.2)	1.55 (1.34–1.94)^*	<0.0001
PTT	30 (26.38–36.63)^,^*	27.15 (23.78–30.35)	44.25 (39.83–63.23)^*	<0.0001
Platelet count	224 (191–280)	258 (213–311)	205 (124–284)^*	0.0093
Fibrinogen	173 (114–204)^*	234 (190–294)	123 (100–158)^*	0.0018
D-dimer	2.96 (2.12–9.55)	2.28 (0.52–11.88)	19.86 (7.33–20.01)	0.0968
6-hr RBCs	0 (0–6)^,^*	0 (0–1)	13 (7–23)^*	<0.0001
6-hr plasma	2 (0–4)^,^*	0 (0–1)	7 (3–12)^*	<0.0001
6-hr platelets	0 (0–1)^,^*	0 (0–0)	1 (1–2)^*	<0.0001
6-hr cryo	0 (0–0)^**	0 (0–0)	0 (0–2)^*	<0.0001

p < 0.05 compared to PHYS,

^**

p < 0.05 compared to HYPER.

Patients who had hyperfibrinolysis received increased blood product transfusions and also had more abnormal conventional coagulation assay values. Differences between groups were identified with the Kruskal-Wallis test for continuous variables and the χ² test for categorical variables. Dunn’s multiple comparisons were used for pairwise two-sided multiple comparison analysis.

Cryo, cryoprecipiate.