Table III.

Areas of positive correlations between white matter volume and BMI

Region	Without HT controlled					With HT controlled
	MNI coordinates			t value	Cluster size	MNI coordinates			t value	Cluster size
	x	y	z			x	y	z
R orbital frontal	13	54	−14	5.58	6102	12	51	−14	5.64	12683
R inferior frontal	35	31	1	3.66	392
R superior frontal	15	57	12	3.06	17
R middle frontal	32	18	46	3.26	25	31	20	46	3.23	34
R middle frontal				n.s.		31	27	36	3.06	27
L orbital frontal	−14	53	−14	3.71	118	−14	53	−14	3.23	177
L superior frontal				n.s.		−16	58	9	3.80	115
L temporal stem	−32	−12	−13	5.03	5217	−32	−12	−13	5.31	6517
R temporal stem	39	−1	−31	3.68	909	39	−1	−31	3.67	933
R superior temporal	35	−27	6	3.51	1497	35	−27	6	3.52	2701
R posterior cingulate				n.s.		22	−57	20	3.37	298
R cingulate				n.s.		9	−6	41	3.87	856
L parietal	−16	−35	59	4.05	197	−16	−35	59	3.90	330
	−21	−43	58	3.60	22
L parietal/temporal	−39	−56	21	3.79	727	−40	−57	23	3.97	2356
	−24	−69	33	3.15	176
L parietal (precuneus)				n.s.		−20	−60	52	3.25	132
L occipital				n.s.		−21	−82	−10	2.96	187

Areas of significant positive correlations between white matter volume and BMI controlling for age and intracranial vault from two analyses with and without including hypertension (HT) as a covariate in the regression analysis. The coordinates of the location of maximal significance [from Montreal Neurological Institute (MNI) template], the t value, and volume (in mm³) of each cluster are provided. R: right hemisphere; L: left hemisphere.