Table I.
Overview of the fMRI results obtained with the two processing methods
| Patient | Epilepsy type | Number of spikes during EEG‐fMRI | Conventional EEG‐fMRI | EEG‐fMRI based on ICA | General comment | Agreement between Conventional and ICA based EEG‐fMRI | ||||
|---|---|---|---|---|---|---|---|---|---|---|
| Position (mm) | Volume (mm3) | Max Z‐score | Position (mm) | Volume (mm3) | Max Z‐score | |||||
| 1 | Multiple tubersclerosis complex, two large calcified hamartomas (right frontal lobe, left operculum) | 63 | (−28,4,4) | 3984 | 4.2 | (−22,−25,−53) | 44,120 | 5.04 | Positive, located interior to the left hamartoma | yes |
| (1,−60,38) | 25,880 | 4.98 | Negative | no | ||||||
| 2 | Multifocal cryptogenic epilepsy without focal lesion | 27 | (47,24,−5) | 2192 | 4.58 | (47,17,−3) | 12,784 | 5.83 | positive | yes |
| 3 | Frontal lobe epilepsy | 127 | (−62,−46,9) | 5,200 | 3.43 | (−62,−42,7) | 8,328 | 4.23 | positive ipsolateral | yes |
| (55,−56,19) | 5,584 | 3.52 | (55,−60,−19) | 8,680 | 3.93 | positive contralateral | yes | |||
| 4 | Cortical dysplasia, right hemisphere parietal and central | 20 | (23,−79,43) | 14,768 | 5.16 | (18,−60,21) | 80,304 | 8.14 | Positive, right parietal | yes |
| cortical | 7.4 | cortical | too spread | 12.5 | negative | yes | ||||
| 5 | Cryptogenic focal epilepsy, ictal SPECT shows left frontal lobe hiper‐perfusion | 19 | (−54,−1,11) | 9,528 | 5.11 | (−62,−3,12) | 4,856 | 5.9 | positive ipsilateral (left) | yes |
| (58,4,12) | 10,896 | 5.21 | (60,2,11) | 9,120 | 5.94 | positive contralateral (right) | yes | |||
| (4,−69,8) | 24,000 | 4.09 | (0,−60,7) | 14,560 | 4.81 | positive occipital | yes | |||
| 6 | Parieto‐occipital epilepsy | 148 | (3,−55,31) | 25,088 | 4.28 | Positive | no | |||
| 7 | Right mesial sclerosis | 256 | (37,0,−13) | 14,296 | 4.98 | (36,−1,−17) | 16,736 | 5.27 | Positive | yes |
| (6,19,−5) | 19,712 | 4.17 | positive (ICA1) | no | ||||||
| 8 | Left mesial sclerosis | 14 | (−32,−3,−29) | 7,376 | 4.59 | positive ipsilateral (right) | no | |||
| (−10,−83,19) | 20,728 | 5.08 | positive occipital | no | ||||||
| 9 | Left mesial sclerosis | 105 | (30,34,19) | 8,488 | 3.63 | positive (right spikes) | no | |||
| (52,−13,34) | 7,240 | 3.52 | positive (right spikes) | no | ||||||
Positions are given in mm in MNI space, and correspond to the center of the activated region. Where columns are left blank, no activation was found. The column “General comment” indicates whether the activation is positively or negatively correlated with the neural activity and whether, if positive, it refers to activity in the region with expected lateralization or elsewhere. Agreement was considered positive when significant overlap between the patches of activation was observed