Table 2:

Clinical Features of Patients with PCD and PID

	PCD (n=27) n (%)	PID (n=32) n (%)	p-value	Sens (%)	Spec (%)
4 key clinical features of PCD [3]
Neonatal respiratory distress despite term birth†	19 (70)	1 (3)	p <0.0001*	70.4	96.9
Daily, year-round wet cough starting before 6 months old	26 (96)	3 (9)	p <0.0001*	96.2	90.6
Daily, year-round nasal congestion starting before 6 months old	25 (93)	3 (9)	p < 0.0001*	92.6	90.6
Any organ laterality defect	18 (67)	1 (3)	p< 0.0001*	66.6	96.1
Daily, year-round wet cough AND daily, year round nasal congestion	24	3	p < 0.0001*	88.9	90.6
Neonatal respiratory distress AND any organ laterality defect	13	0	p< 0.0001*	48.1	100
1 key PCD clinical feature	27 (100)	8 (25)	p< 0.0001*
≥ 2 key PCD clinical features	27 (100)	5 (16)	p < 0.0001*
Other Clinical Features in Adults With PCD [40]
Bronchiectasis on CT chest	14 (88) (n=16)	8 (38) (n=21)	p = 0.003 *
Pansinusitis on CT sinus	8 (57) (n=14)	5 (42) (n=12)	p = 0.7

^†Neonatal respiratory distress defined as need for supplemental oxygen or positive pressure support for more than 24 hours, despite term birth

^*Statistically significant value using Fisher exact test

Abbreviations- PCD: Primary Ciliary Dyskinesia; PID: primary immunodeficiency; sens: sensitivity; spec: specificity; CT: computed tomography