Table III.
BOLD‐signal characteristics and Euclidean coordinates of SI, SII, and thalamic activations
| Subjects | Stimulation | Activation | n | r | ΔS | x | y | z |
|---|---|---|---|---|---|---|---|---|
| Controls (n = 13) | Lips | SI (c) | 26 | 0.63 ± 0.10 | 1.05 ± 0.46 | 54 ± 3 | −15 ± 7 | 37 ± 5 |
| SII (c) | 23 | 0.50 ± 0.09 | 0.73 ± 0.51 | 52 ± 7 | −21 ± 9 | 21 ± 6 | ||
| Thalamus (c) | 21 | 0.40 ± 0.09 | 0.52 ± 0.30 | 15 ± 6 | −19 ± 7 | 7 ± 5 | ||
| SI (i) | 26 | 0.50 ± 0.09 | 0.83 ± 0.45 | 55 ± 4 | −14 ± 10 | 35 ± 6 | ||
| SII (i) | 21 | 0.44 ± 0.09 | 0.62 ± 0.23 | 53 ± 7 | −23 ± 10 | 21 ± 5 | ||
| Thalamus (i) | 17 | 0.38 ± 0.08 | 0.51 ± 0.41 | 13 ± 2 | −20 ± 7 | 7 ± 5 | ||
| Fingers | SI (c) | 25 | 0.72 ± 0.11 | 1.34 ± 0.69 | 49 ± 4 | −18 ± 10 | 46 ± 4 | |
| SII (c) | 26 | 0.58 ± 0.13 | 0.87 ± 0.34 | 48 ± 6 | −19 ± 6 | 18 ± 6 | ||
| Thalamus (c) | 24 | 0.40 ± 0.09 | 0.40 ± 0.20 | 14 ± 5 | −18 ± 6 | 7 ± 4 | ||
| SI (i) | 18 | 0.49 ± 0.17 | 0.73 ± 0.47 | 47 ± 7 | −19 ± 7 | 48 ± 6 | ||
| SII (i) | 25 | 0.47 ± 0.12 | 0.59 ± 0.28 | 52 ± 6 | −20 ± 7 | 20 ± 6 | ||
| Thalamus (i) | 17 | 0.33 ± 0.09 | 0.32 ± 0.12 | 11 ± 4 | −18 ± 6 | 8 ± 4 | ||
| Patients with TN (n = 18) | Lips | SI (c) | 35 | 0.56 ± 0.12 | 0.66 ± 0.33 | 52 ± 5 | −16 ± 5 | 38 ± 8 |
| SII (c) | 33 | 0.47 ± 0.09 | 0.46 ± 0.24 | 50 ± 8 | −21 ± 9 | 22 ± 8 | ||
| Thalamus (c) | 26 | 0.37 ± 0.09 | 0.32 ± 0.12 | 13 ± 4 | −15 ± 8 | 6 ± 6 | ||
| SI (i) | 28 | 0.46 ± 0.13 | 0.47 ± 0.21 | 52 ± 6 | −17 ± 4 | 38 ± 8 | ||
| SII (i) | 34 | 0.45 ± 0.10 | 0.55 ± 0.39 | 52 ± 9 | −22 ± 9 | 24 ± 8 | ||
| Thalamus (i) | 23 | 0.39 ± 0.09 | 0.38 ± 0.18 | 13± 5 | −15 ± 6 | 8 ± 6 | ||
| Fingers | SI (c) | 32 | 0.53 ± 0.17 | 0.72 ± 0.37 | 48 ± 8 | −19 ± 5 | 47 ± 5 | |
| SII (c) | 33 | 0.44 ± 0.11 | 0.47 ± 0.19 | 48 ± 7 | −23 ± 10 | 21 ± 6 | ||
| Thalamus (c) | 22 | 0.39 ± 0.10 | 0.38 ± 0.18 | 12 ± 4 | −17 ± 5 | 5 ± 4 | ||
| SI (i) | 15 | 0.34 ± 0.09 | 0.35 ± 0.16 | 48 ± 7 | −20 ± 5 | 45 ± 6 | ||
| SII (i) | 30 | 0.40 ± 0.11 | 0.43 ± 0.27 | 50 ± 8 | −22 ± 12 | 22 ± 7 | ||
| Thalamus (i) | 17 | 0.36 ± 0.10 | 0.37 ± 0.25 | 12 ± 6 | −16 ± 6 | 7 ± 5 | ||
| Patients post‐OP (n = 10) | Lips | SI (c) | 20 | 0.53 ± 0.16 | 0.77 ± 0.56 | 54 ± 6 | −15 ± 6 | 40 ± 8 |
| SII (c) | 17 | 0.43 ± 0.11 | 0.41 ± 0.13 | 51 ± 8 | −19 ± 7 | 26 ± 7 | ||
| Thalamus (c) | 14 | 0.37 ± 0.10 | 0.52 ± 0.43 | 12 ± 5 | −16 ± 6 | 7 ± 6 | ||
| SI (i) | 10 | 0.47 ± 0.14 | 0.64 ± 0.23 | 56 ± 3 | −17 ± 7 | 38 ± 4 | ||
| SII (i) | 20 | 0.40 ± 0.11 | 0.38 ± 0.14 | 54 ± 5 | −21 ± 12 | 27 ± 7 | ||
| Thalamus (i) | 10 | 0.37 ± 0.10 | 0.38 ± 0.35 | 12 ± 5 | −19 ± 6 | 7 ± 6 | ||
| Fingers | SI (c) | 20 | 0.59 ± 0.18 | 0.96 ± 0.56 | 47 ± 7 | −20 ± 5 | 49 ± 6 | |
| SII (c) | 17 | 0.49 ± 0.13 | 0.58 ± 0.26 | 48 ± 8 | −22 ± 7 | 22 ± 6 | ||
| Thalamus (c) | 17 | 0.36 ± 0.06 | 0.35 ± 0.15 | 14 ± 5 | −15 ± 3 | 7 ± 4 | ||
| SI (i) | 6 | 0.36 ± 0.09 | 0.45 ± 0.22 | 49 ± 11 | −23 ± 6 | 47 ± 4 | ||
| SII (i) | 18 | 0.42 ± 0.12 | 0.43 ± 0.20 | 53 ± 9 | −23 ± 12 | 27 ± 7 | ||
| Thalamus (i) | 12 | 0.36 ± 0.06 | 0.34 ± 0.06 | 12 ± 4 | −15 ± 5 | 7 ± 4 |
Correlations of the measured BOLD‐signals to the applied hemodynamic reference function (r). Relative BOLD‐signal changes (ΔS%) and Euclidean coordinates of COGs (x, y, z) are depicted for contra‐ (c) and ipsilateral (i) SI, SII, and thalamic activations for each sensory paradigm in control subjects, patients with TN (right and left side) and patients with TN after neurosurgical intervention (post‐OP). Data from right and left stimulation sides were pooled and X‐coordinates all transferred into positive values. Data are given as mean ± SD.