Table I.
Demographic and neuropsychological data of healthy elderly (Nold) and amnesic mild cognitive impairment (MCI) subjects
| MCI C+ | MCI C− | Nold | |
|---|---|---|---|
| N | 28 | 29 | 28 |
| Age (years) | 77 (± 1.0 SE) | 73 (± 1.5 SE) | 73.2 (±1.2 SE) |
| Education (years) | 8 (± 0.6 SE) | 8 (± 0.8 SE) | 8.2 (± 0.8 SE) |
| Gender (M/F) | 12/16 | 14/15 | 12/16 |
| MMSE | 26.6 (± 0.3 SE) | 26.2 (± 0.3 SE) | 28.4 (± 0.2 SE) |
| ApoE4 (%) | 28 | 38 | — |
| Lesion of cholinergic white matter (cm3) | 0.933 (± 0.180 SE) | 0.027 (± 0.005 SE) | — |
Of note, the MCI group was divided in two sub‐groups: the MCI subjects with low degree of cholinergic lesion (MCI Ch−, cholinergic lesional load <0.0065) and MCI subjects with high degree of cholinergic lesion (MCI Ch+, cholinergic lesional load >0.0065).