Table I.
Main demographic and clinical characteristics of healthy controls, patients with amnestic mild cognitive impairment (aMCI), and patients with Alzheimer's disease (AD)
| Healthy controls | aMCI patients | AD patients | P * | |
|---|---|---|---|---|
| Number of subjects | 11 | 15 | 10 | – |
| Men/Women | 4/6 | 5/10 | 2/8 | n.s. |
| Mean age (range) [years] | 65.6 (54–77) | 66.8 (41–79) | 69.1 (52–84) | n.s. |
| Median disease duration (range) [years] | – | 2.8 (0.5–5.0) | 2.9 (1.0–5.0) | n.s. |
| Median MMSE (range) | 28 (27–30) | 27 (23–28) | 17 (12–25) | <0.001** |
| Median CDR (range) | 0.0 (0.0–0.0) | 0.5 (0.5–0.5) | 1.0 (1.0–2.0) | <0.001** |
| Mean maximum finger tapping frequency for 30‐s trial (range) | 1.6 (1.4–1.9) | 1.6 (1.2–1.9) | 1.5 (1.1–1.8) | n.s. |
Abbreviations: aMCI = amnestic mild cognitive impairment; AD = Alzheimer's disease; MMSE = Mini Mental State Examination; CDR = Clinical Dementia Rating scale.
Analysis of covariance (ANCOVA) between groups. See text for further details.
Adjusted for age.