Table III.

Significant paths coefficients (mean values) between brain regions of healthy controls, patients with amnestic mild cognitive impairment (aMCI), and patients with Alzheimer's disease (AD)

	Connection strength
	Healthy controls	aMCI patients	AD patients
R primary SMC—L primary SMC	0.09	0.009*	0.05
L primary SMC—Head of L caudate nucleus	−0.06	−0.09	−0.2**
Head of L caudate nucleus—L primary SMC	−0.02	−0.03	−0.09**
Head of L caudate nucleus—Cingulum	−0.04	−0.009	−0.06**
Cingulum—L primary SMC	−0.004	0.01	0.09**

Abbreviations: L = left, R = right, SMC = sensorimotor cortex, aMCI = amnestic mild cognitive impairment; AD = Alzheimer's disease.

Only connections significantly different in at least one between‐group comparison have been reported.

Note that positive values have to be interpreted as direct coupling of activity between the two areas, while negative values have to be interpreted as an inverse coupling of activity.

^*Significantly different between healthy controls and aMCI patients (P < 0.05).

^**Significantly different between aMCI and AD patients (P < 0.05).