Table II.
Anatomical locations and center of gravity coordinates (in Talairach space) displayed for brain regions that demonstrated significant correlations with each of the six insula ROIs
| ROI | Anatomical location (center of gravity) | Talairach coordinates | Voxels | ||
|---|---|---|---|---|---|
| x | y | z | |||
| LaIC | Left insula | −37 | 14 | 1 | 24,023 |
| Left cingulate gyrus BA 24/32 (pACC/aMCC) | −7 | 33 | 26 | 580 | |
| Left cingulate gyrus/BA 24 (pMCC) | −6 | 6 | 41 | 1,419 | |
| Left cerebellum | −4 | −29 | −15 | 125 | |
| Left inferior frontal gyrus/BA 9 | −34 | 8 | 28 | 189 | |
| Right insula | 33 | −26 | −12 | 14,420 | |
| Right inferior parietal lobule/BA 40 | 51 | −41 | 34 | 825 | |
| Right fusiform gyrus/BA 37 | 42 | −40 | −13 | 840 | |
| Right angular gyrus/BA 39 | 39 | −57 | 37 | 143 | |
| Right paracentral/inferior parietal gryus/BA 2/40 | 21 | −41 | 58 | 631 | |
| Right cerebellum | 3 | −68 | −24 | 472 | |
| Right cingulate gyrus BA 24/32 (pACC/aMCC) | 4 | 31 | 31 | 856 | |
| Right cingulate gyrus/BA 24 (pMCC) | 5 | 5 | 40 | 608 | |
| Right cingulate gyrus/BA31 (pMCC) | 6 | −41 | 43 | 147 | |
| LmIC | Left insula | −36 | −7 | 12 | 31,545 |
| Left postcentral gyrus/BA 2/BA 40 (S2) | −46 | −18 | 27 | 2,834 | |
| Left postcentral gyrus/BA 1, 2, 3 (S1) | −16 | −39 | 62 | 1,314 | |
| Left cingulate gyrus/BA 24 (pMCC) | −7 | −9 | 46 | 1,479 | |
| Left precentral gyrus/BA 4 | −44 | −14 | 43 | 1,892 | |
| Left lingual gyrus/BA 18 | −9 | −71 | 6 | 210 | |
| Left middle frontal gyrus/BA 10 | −31 | 38 | 7 | 151 | |
| Right insula | 32 | −6 | 10 | 16,793 | |
| Right inferior parietal/postcentral gyrus/BA 40 (S2) | 42 | −23 | 27 | 3,033 | |
| Right postcentral gyrus/BA 2/40 | 28 | −42 | 47 | 4,023 | |
| Right cingulate gyrus/BA 24 (pMCC) | 7 | −2 | 47 | 702 | |
| Right precentral gyrus/BA 4 | 38 | −18 | 46 | 2,344 | |
| Right fusiform gyrus/BA 37 | 42 | −41 | −9 | 234 | |
| Right inferior frontal gyrus/BA9 | 36 | 8 | 22 | 138 | |
| Right fusiform gyrus/BA 37 | 36 | −53 | −3 | 310 | |
| Right cuneus/BA 30 | 21 | −71 | 7 | 566 | |
| LpIC | Left insula | −37 | −17 | 10 | 48,422 |
| Left inferior parietal gyrus/BA 2/BA 40 (S2) | −40 | −23 | 25 | 3,257 | |
| Left medial frontal gyrus/BA 6 | −10 | −11 | 67 | 338 | |
| Left cingulate gyrus/BA 31 (pMCC) | −10 | −11 | 46 | 806 | |
| Left precuneus/BA 7 | −10 | −56 | 46 | 252 | |
| Left cuneus/BA 18 | −16 | −83 | 16 | 520 | |
| Left inferior parietal lobule/BA 40 | −22 | −35 | 52 | 371 | |
| Left postcentral gyrus/BA 2 | −41 | −29 | 45 | 1,240 | |
| Left precentral gyrus/BA 4 | −36 | −16 | 53 | 471 | |
| Left middle temporal gyrus/BA 37 | −43 | −59 | −3 | 324 | |
| Right insula | 36 | −14 | 10 | 29,659 | |
| Right inferior parietal gyrus/BA 2/BA 40 (S2) | 42 | −23 | 25 | 2,319 | |
| Right precentral gyrus/BA 1, 2, 3 (S1) | 36 | −20 | 37 | 272 | |
| Right occipital lobe, sub‐gyral, white matter | 36 | −59 | −3 | 226 | |
| Right cingulate gyrus/BA 24 (pMCC) | 2 | −7 | 49 | 330 | |
| Right postcentral gyrus/BA 1, 2, 3 (S1) | 25 | −38 | 52 | 1,121 | |
| Right precuneus/BA 31 | 30 | −71 | 16 | 1,724 | |
| RaIC | Right insula | 39 | 17 | 4 | 12,460 |
| Right middle frontal gyrus/BA 9 | 30 | 32 | 37 | 308 | |
| Right/left cingulate gyrus/BA 24/32 (pACC/aMCC) | 5 | 32 | 27 | 1,118 | |
| Right cingulate gyrus (GC)/BA 24 (pMCC) | 6 | 13 | 38 | 672 | |
| Left insula | −40 | 14 | 1 | 8,075 | |
| Left cingulate gyrus/BA 24 (pACC/aMCC) | −6 | 36 | 26 | 128 | |
| Left cingulate gyrus/BA 24 (pMCC) | −4 | 9 | 40 | 325 | |
| RmIC | Right insula | 39 | 2 | 4 | 42,546 |
| Right postcentral gyrus/BA 1, 2, 3 (S1) | 36 | −19 | 25 | 371 | |
| Right precentral gyrus/BA 6 | 36 | 5 | 22 | 134 | |
| Right inferior frontal gyrus/BA 46 | 33 | 35 | 10 | 199 | |
| Right fusiform gyrus/BA 19 | 36 | −53 | −6 | 139 | |
| Right parahippocampal gyrus/BA 27 | 24 | −32 | −3 | 139 | |
| Right cuneus/BA 31/17 | 12 | −71 | 10 | 260 | |
| Right cingulate gyrus/BA 24 (pMCC) | 1 | −2 | 48 | 978 | |
| Left insula | −37 | 2 | 10 | 27,661 | |
| Left cingulated gyrus/BA 24 (pMCC) | −4 | −2 | 46 | 981 | |
| Left cuneus/BA 31/17 | −13 | −68 | 10 | 347 | |
| Left postcentral gyrus/BA 40/42 (S2) | −40 | −19 | 18 | 460 | |
| Left cuneus/BA 18 | −19 | −80 | 25 | 155 | |
| RpIC | Right insula | 36 | −14 | 10 | 40,701 |
| Right postcentral gyrus/BA 40 (S2) | 40 | −20 | 20 | 901 | |
| Right precentral gyrus/BA 4 | 42 | −19 | 44 | 1,539 | |
| Right medial temporal gyrus/BA 37 | 42 | −62 | 10 | 149 | |
| Left cuneus/BA 30 | −13 | −68 | 10 | 2,776 | |
| Right postcentral gyrus/BA 1, 2, 3 (S1) | 18 | −35 | 61 | 277 | |
| Right cingulate gyrus/BA 24/32 (pMCC) | 6 | −1 | 46 | 330 | |
| Left insula | −40 | −8 | 10 | 24,915 | |
| Left paracentral/cingulate gyrus/BA 24 (pMCC/aPCC) | −7 | −26 | 43 | 1,371 | |
| Left superior frontal gyrus/BA 6 | −10 | −14 | 67 | 329 | |
| Left cuneus/BA 17 | −16 | −83 | 10 | 367 | |
| Left postcentral gyrus/BA 40 (S2) | −40 | −18 | 19 | 726 | |
Brain areas were derived from the multisubject conjunction analyses, thresholded at a corrected P < 0.05. Voxels are reported as 1 × 1 × 1 mm3. aIC, anterior insula; mIC, mid‐insula; pIC, posterior insula; pACC, pregenual anterior cingulate cortex; aMCC, anterior mid‐cingulate cortex; pMCC, posterior mid‐cingulate cortex; S1, primary somatosensory cortex; S2, secondary somatosensory cortex; R, right; L, left.