Fig. 1.

mRNA and protein expression of FBLN5 in the lens capsule of cases and controls. a FBLN5 expression was found to be significantly downregulated in PEXS (0.53 ± 0.1) compared to that of control (1 ± 0.1) with a p-value of 0.04 but not in PEXG subjects (0.73 ± 0.1, p = 0.34). b Represents immunoblots for FBLN5 protein expression in the lens capsule of control versus PEXS and PEXG subjects. c Quantitative analysis of FBLN5 protein in control versus PEXS and PEXG subjects. Compared to lens capsule of control (1 ± 0.2), in PEXS (0.26 ± 0.04) subjects there is a significantly decreased (p = 0.04) FBLN5 expression. However, there is no significant (p = 0.36) difference in the FBLN5 protein level between control and PEXG (0.66 ± 0.2) subjects. Sample size is denoted by “n” and relative expression change in fold is represented as mean ± SEM. Each experiment is repeated at least three times. Student’s t-test was used to calculate the statistical significance between groups, *p < 0.05