Table I.
Brain region | Brodmann area(s) | Number of voxels in cluster | Z‐score at peak voxel | MNI coordinates of peak voxel (x, y, z) | ||
---|---|---|---|---|---|---|
Brain regions demonstrating significant activation in response to being liked | ||||||
Midline cortical activations | ||||||
Ventromedial prefrontal | 10, 32 | 519 | 4.6 | 0 | 60 | −4 |
10 | 173 | 4.4 | −4 | 68 | 10 | |
Pregenual anterior cingulate | 24 | 12 | 3.4 | 8 | 36 | 4 |
Mid cingulate | 23 | 238 | 5.2 | 2 | −10 | 22 |
Dorsal posterior cingulate | 23 | 34 | 3.5 | 0 | −32 | 28 |
Retrosplenial posterior cingulate | 26, 29 | 11 | 3.3 | −6 | −46 | 14 |
Precuneus/ventral posterior cingulate | 31 | 60 | 3.9 | 2 | −66 | 20 |
Left hemisphere cortical activations | ||||||
Superior frontal | 8 | 92 | 3.8 | −24 | 42 | 40 |
8 | 15 | 3.3 | −24 | 28 | 48 | |
9 | 14 | 3.4 | −22 | 44 | 26 | |
Inferior temporal | 21 | 11 | 3.9 | −62 | −10 | −22 |
Lateral parietal | 39 | 11 | 3.5 | −42 | −60 | 44 |
Fusiform | 18, 19 | 235 | 4.6 | −22 | −78 | −20 |
Occipital | 17 | 348 | 5.6 | −18 | −100 | 0 |
Right hemisphere cortical activations | ||||||
Superior frontal | 9 | 12 | 3.5 | 22 | 60 | 26 |
Anterior insula/operculum | 13 | 157 | 4.2 | 38 | 14 | −18 |
Inferior temporal | 20, 21 | 46 | 3.8 | 64 | −12 | −24 |
Occipital/fusiform | 17, 18, 19 | 602 | 5.0 | 16 | −96 | −2 |
Subcortical and cerebellar activations | ||||||
R NAcc | 8 | 3.4 | 4 | 6 | −4 | |
L amygdala | 25 | 3.8 | −24 | −10 | −24 | |
R amygdala | 13 | 3.3 | 30 | −8 | −22 | |
Ventral tegmental area | 4 | 3.3 | 0 | −20 | −18 | |
Cerebellum | 10 | 3.4 | 26 | −48 | −24 |
Voxels were thresholded at P < 0.001 (uncorrected), and formed clusters of at least 8 contiguous voxels.
An exception was made for the ventral tegmental area, whose anatomical volume is less than the volume represented by eight voxels [Mai et al.,2007].