Figure 2.

Patterns of activation illustrating interaction effects between group (healthy elderly subjects (Control) vs. Alzheimer's disease patients (AD)) and list conditions associated with processing phonological material (WL+ nonwords > vowels repetition, WL− nonwords > vowels repetition, WL+ nonwords > WL− nonwords). The resulting set of voxels for each contrast was thresholded at P ≤ 0.001 (uncorrected). Then small volume correction was applied on published coordinates for a priori regions considered to be involved in phonological processing in healthy young subjects. The interactions illustrating reduced activation in AD patients relative to elderly controls are shown in green, while the interactions illustrating greater activation in AD patients relative to elderly controls are shown in red. On the right side of the figure, mean values of the parameter estimates in the right precentral gyrus [72, −14, 20] and the left inferior [−62, −12, −28] and superior [−48, −12, −4] temporal gyri (from up to bottom) are plotted.