Mean activation (IWV ± SEM) elicited by infant vocalizations in amygdala (A) and cingulate cortex (B, C). Activations for laughing and crying, as well as for, the alienated control stimuli are collapsed, which corresponds to subjective ratings of stimulus' naturalness. In women, natural laughing and crying elicited stronger activation in amygdala and ACC than unnatural stimuli. In men, unnatural laughing and crying elicited stronger activation in ACC and PCC than natural stimuli, and to a lesser extent in the amygdala.