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The crystal structure for GluN1/GluN2B receptors is shown in the left panel 13 depicting the amino-terminal domain (ATD), the agonist-binding domain (ABD), and the transmembrane domain (TMD). Not shown is the intracellular carboxyl-terminal domain (CTD). The right panel displays a schematic of a GRIN subunit, and the subdomains and the clamshell features of the ATD and ABD are indicated.
