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. Author manuscript; available in PMC: 2020 Aug 1.
Published in final edited form as: Leuk Res. 2019 Jun 17;83:106172. doi: 10.1016/j.leukres.2019.106172

Fig. 1.

Fig. 1.

Oprozomib with low-dose dexamethasone dosing schedule (14-day cycle). NA, not available. a Cohort 2 in the 5/14 schedule represents patients who were given the starting oprozomib dose of 210 mg for the 5/14 schedule. The dose was de-escalated by 30 mg for cohort 1, and cohort 3 represents patients who were given the step-up oprozomib dosing of 150/180 mg. b Cohort 1 in the 2/7 schedule represents patients who were given the starting oprozomib dose of 210 mg for the 2/7 schedule; each subsequent cohort on the 2/7 schedule was given higher oprozomib doses in 30 mg increments.