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Patient disposition.
| 5/14 schedule 150–210 mg/day OPZ |
2/7 schedule 210–330 mg/day OPZ |
|
|---|---|---|
| Number of patients enrolled | 19 | 46 |
| Continuing treatment | 0 | 8 (17.4) |
| Discontinued treatment | 19 (100) | 38 (82.6) |
| Adverse event | 11 (57.9) | 12 (26.1) |
| Disease progression | 5 (26.3) | 19 (41.3) |
| Lost to follow-up | 0 | 1 (2.2) |
| PI decision | 1 (5.3) | 2 (4.3) |
| Patient request | 2 (10.5) | 4 (8.7) |
OPZ, oprozomib; PI, principal investigator.
