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. Author manuscript; available in PMC: 2020 Dec 1.
Published in final edited form as: J Immunol. 2019 Dec 1;203(11):2757–2769. doi: 10.4049/jimmunol.1900901

Figure 1. Inflammasomes in the chorioamniotic membranes during normal parturition.

Figure 1.

Representative image of the chorioamniotic membranes (amnion, chorion, and decidua) surrounding the amniotic cavity containing the fetus and amniotic fluid. The NLRP1, AIM2, NLRC4 and NLRP3 sensor molecules have been detected in the chorioamniotic membranes during normal pregnancy. The activation of the NLRP3 inflammasome leading to pyroptosis has been implicated in the physiological mechanisms of term parturition.