Table IV.
Distinct regions showing increased MR signal intensity in the new sequence and new map conditions
| Region (BA) | Left hemisphere | Region (BA) | Right hemisphere | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| t | Talairach coordinates | Volume (μl) | r RT | t | Talairach coordinates | Volume (μl) | r RT | ||||||
| x | y | z | x | y | z | ||||||||
| New sequence (visuomotor learning) | |||||||||||||
| Frontal lobe | |||||||||||||
| [1] SMA (6) | 5.1d | −12 | −10 | 52 | 242 | [7] Premotor (6) | 2.2a | 19 | −5 | 57 | 617 | ||
| [2] Premotor (6) | 3.6c | −23 | −17 | 55 | 216 | [8] Inferior frontal (44) | 1.9a | 50 | 9 | 21 | 273 | ||
| [3] Middle frontal (10) | 3.1c | −31 | 43 | 19 | 437 | ||||||||
| Cingulate cortex | |||||||||||||
| [9] Anterior cingulate (24) | 3.3c | 11 | −16 | 36 | 204 | ||||||||
| Occipital lobe | |||||||||||||
| [4] Inferior occipital (18) | 2.6c | −23 | −89 | −8 | 521 | [10] Middle occipital (18) | 4.2c | 26 | −84 | −7 | 916 | ||
| 2.1a | −37 | −83 | −2 | 369 | 0.63 | [11] Inferior occipital (18/19) | 2.9c | 37 | −68 | −2 | 334 | ||
| [12] Middle occipital (19) | 3.7c | 49 | −75 | 9 | 452 | ||||||||
| Subcortical | |||||||||||||
| [5] Thalamus (VPL) | 3.7c | −15 | −16 | 4 | 583 | 0.60 g | [13] Thalamus (DM) | 1.7a | 8 | −21 | 12 | 689 | |
| [6] Caudate | 2.5b | −9 | 8 | 14 | 341 | 0.56 g | |||||||
| Cerebellumh | |||||||||||||
| [14] Lobule VI | 2.4b | 37 | −48 | −23 | 700 | ||||||||
| [15] Lobule IV | 2.9c | 22 | −27 | −30 | 270 | ||||||||
| New map (spatial learning) | |||||||||||||
| Parietal/occipital lobe | |||||||||||||
| [16] Sup occipital (19) + Precuneus (31) | −1.7e | −27 | −74 | 25 | 689 | 0.51 f | |||||||
Numbers in brackets refer to locations of unique activation foci in Figure 7.
P < 0.05;
P < 0.025;
P < 0.01;
P < 0.001;
P = 0.054;
paired t‐tests comparing the magnitude of the fMRI signal (transfer condition minus familiar condition) between the two transfer conditions.
P < 0.01;
P < 0.005 for unique regions, correlations are also displayed for those that approached significance.
Regions identified using the atlas of Schmahmann et al. [2000].