Table II.
Main regional loci of brain activation by meta‐analysis of n‐back working memory task variants in functional neuroimaging
| Region (BA) | x | y | z | ALE | Volume (mm3) |
|---|---|---|---|---|---|
| All n‐back working memory dataa | |||||
| Lateral premotor (6) | 28 | 4 | 50 | 0.0684 | 16,608 |
| −26 | 0 | 52 | 0.0488 | 3,016 | |
| −44 | −2 | 38 | 0.0361 | ? | |
| Dorsal cingulate/medial premotor (SMA) (32,6) | −2 | 12 | 42 | 0.0600 | |
| Dorsolateral prefrontal (46,9) | 40 | 32 | 30 | 0.0515 | 8,120 |
| −36 | 44 | 20 | 0.0267 | 992 | |
| −44 | 18 | 22 | 0.0422 | 1,2024 | |
| Ventrolateral prefrontal (45,47) | −30 | 18 | 6 | 0.0244 | |
| 32 | 20 | 4 | 0.0267 | 992 | |
| Frontal pole (10) | −36 | 44 | 20 | 0.0267 | 1,744 |
| Medial posterior parietal (7) | 10 | −66 | 48 | 0.0555 | 13,776 |
| Inferior parietal lobule (40) | −36 | −50 | 40 | 0.0551 | |
| 40 | −48 | 38 | 0.0535 | 8,096 | |
| Medial cerebellum | 2 | −64 | −24 | 0.0199 | 104 |
| Verbal stimuli, identity monitoring datab | |||||
| Lateral premotor (6) | 28 | 0 | 52 | 0.0334 | 2,096 |
| −26 | 2 | 52 | 0.0342 | 1,888 | |
| Dorsal cingulate/medial premotor (SMA) (32,6) | −2 | 12 | 42 | 0.0367 | 3,040 |
| Dorsolateral prefrontal (46,9) | 42 | 32 | 30 | 0.0220 | 1,144 |
| Ventrolateral prefrontal (44) | −50 | 12 | 8 | 0.0246 | 5,968 |
| −62 | 0 | 14 | 0.0138 | 216 | |
| Frontal pole (10) | −38 | 44 | 20 | 0.0204 | 896 |
| 36 | 46 | 18 | 0.0214 | 1,240 | |
| Medial posterior parietal (7) | 12 | −64 | 48 | 0.0302 | 1,312 |
| Inferior parietal lobule (40) | 30 | −58 | 42 | 0.0197 | 1,144 |
| 38 | −46 | 38 | 0.0249 | 1,928 | |
| −34 | −48 | 38 | 0.0379 | 5,136 | |
| Medial and lateral cerebellum | 2 | −64 | −24 | 0.0200 | 792 |
| 34 | −56 | −24 | 0.0180 | 768 | |
| 24 | −60 | −44 | 0.0170 | 712 | |
| −26 | −66 | −50 | 0.0163 | 328 | |
| Thalamus | 8 | −14 | 4 | 0.0121 | 208 |
| Nonverbal stimuli, identity monitoring datac | |||||
| Lateral premotor (6/8) | 38 | 20 | 50 | 0.0132 | 416 |
| Dorsal cingulate (32) | 0 | 26 | 36 | 0.0150 | 1,456 |
| Dorsolateral prefrontal (46,9) | 42 | 30 | 24 | 0.0141 | 1,064 |
| −44 | 4 | 32 | 0.0120 | 464 | |
| −40 | 26 | 24 | 0.0133 | 432 | |
| Frontal pole (10) | −32 | 42 | 10 | 0.0124 | 632 |
| −28 | 62 | −4 | 0.0125 | 280 | |
| Inferior parietal lobule (40) | −30 | −54 | 40 | 0.0129 | 792 |
| 58 | −36 | 44 | 0.0119 | 336 | |
| Nonverbal stimuli, location monitoring datad | |||||
| Lateral premotor (6) | 30 | 0 | 48 | 0.0204 | 1568 |
| 16 | 4 | 56 | 0.0124 | 352 | |
| Dorsal cingulate/medial premotor (SMA) (32,6) | 0 | 12 | 42 | 0.0166 | 1,144 |
| Dorsolateral prefrontal (46,9) | 36 | 36 | 24 | 0.0278 | 2,320 |
| Medial posterior parietal (7) | 10 | −58 | 54 | 0.0160 | 1,568 |
| 24 | −60 | 52 | 0.0172 | 824 | |
| 10 | −48 | 64 | 0.0115 | 200 | |
| Inferior parietal lobule (40) | −34 | −58 | 42 | 0.0136 | 704 |
| 42 | −50 | 36 | 0.0192 | 848 |
a
668 coordinates, 24 papers.
b
226 coordinates, 12 papers.
c
76 coordinates, 6 papers.
d
150 coordinates, 5 papers.
BA, approximate Brodmann area; ALE, activation likelihood estimation.