Table IV.
Groups differentiating principal components (PCs)
PC | Core areas anatomical name | Coordinates1 | PC loads | Group differences2 | Suggested functional correlate, brain system, pattern | |
---|---|---|---|---|---|---|
Right | Left | |||||
PC1 | Motor hand area | 36/−16/51 | + | Norm‐rest vs. patients‐rest (P < .05) | Sensorimotor control | |
Sensory hand area | 31/−32/50 | + | ||||
Premotor area | 36/0/46 | + | ||||
Suppl. motor area | 7/4/53 | + | ||||
Lobulus parietalis superior | 30/−56/49 | −22/−58/48 | + | |||
Precuneus | 8/−52/43 | −4/−45/43 | + | |||
Parietal operculum | −45/−24/19 | + | ||||
Posterior cingulate gyrus | −1/−35/37 | + | ||||
Uncus gyri hippocampi | 12/−2/−25 | −17/−7/−25 | − | |||
Semilunar lobulus | 29/−70/−28 | −24/−71/−28 | − | |||
PC7 | Dorsolateral prefrontal | 46/23/22 | + | Norm‐act vs. patients‐act (P < .02) | Working memory | |
Mesial frontal | 1/45/23 | + | ||||
Medial temporal gyrus | 50/−56/6 | + | ||||
Insular cortex | 46/−9/12 | + | ||||
Med. occipito‐temporal g. | −5/−80/5 | + | ||||
Thalamus, medial‐dorsal | 2/−14/8 | + | ||||
Superior occipital gyrus | 18/−74/6 | − | ||||
PC11 | Posterior cingulate gyrus | −5/−64/11 | + | Patients‐rest vs. norm‐rest (P < .02) | Comparative feature discrimination | |
Angular gyrus | −60/−55/−6 | + | Patients‐act vs. norm‐act (P < .01) | |||
Med. occipito‐temporal g. | 8/−92/−1 | + | Subgroup A‐rest vs. norm‐rest (P < .02) | |||
Superior temporal gyrus | 60/−42/7 | − | Subgroup A‐act vs. norm‐act (P < .01) | |||
Medial frontal gyrus | 32/18/34 | − | ||||
Superior temporal gyrus | −52/−24/1 | − | ||||
Nucleus ruber | 2/−26/−3 | − |
Acc. to Talairach and Tournoux (1988).
Normal volunteers in rest and activation state, norm‐rest and norm‐act; patients in rest and activation state, patients‐rest and patients‐act; patients with normal FDOPA uptake in caudate nucleus, subgroup A; groups with higher expression of PC were indicated first.