Table II.
Talairach co‐ordinates of the activation peaks of regions jointly activated by low and high frequency words as well as the regions active in the contrast between low and high frequency words with each of the experimental designs
| Brain region and Brodmann's area | Block design (size) | Block design (fixation) | Event‐related design | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| x | y | z | F | x | y | z | F | x | y | z | F | |
| Low and high frequency | ||||||||||||
| Frontal | ||||||||||||
| Inferior frontal gyrus (BA 44) | −40 | 13 | 27 | >50 | −46 | 7 | 30 | >50 | −37 | 12 | 27 | 36 |
| 35 | 16 | 26 | 32 | — | — | — | — | 38 | 14 | 30 | 25 | |
| Inferior frontal gyrus (BA 44) | 32 | 22 | 8 | 28 | 37 | 6 | 30 | >50 | 28 | 23 | 9 | 36 |
| Precentral gyrus (BA 4) | — | — | — | — | −43 | −31 | 40 | 40 | 35 | 1 | 30 | >50 |
| Cingulate gyrus/SMA (BA6/24) | −2 | 1 | 47 | >50 | −4 | 3 | 51 | >50 | −6 | 7 | 45 | >50 |
| Temporal | ||||||||||||
| Middle temporal gyrus (BA 21) | −55 | −44 | −3 | >50 | — | — | — | — | — | — | — | — |
| Fusiform gyrus (BA 37) | −43 | −56 | −12 | >50 | * | * | * | −45 | −50 | −9 | >50 | |
| Parietal | ||||||||||||
| Superior parietal lobule (BA 7) | −31 | −65 | 38 | 45 | −26 | −57 | 46 | >50 | −31 | −64 | 44 | 50 |
| 24 | −65 | 40 | >50 | 28 | −67 | 39 | 45 | |||||
| Occipital | ||||||||||||
| Lingual gyrus (BA 18) | — | — | — | — | −40 | −70 | −9 | >50 | −28 | −69 | −9 | >50 |
| Lingual gyrus (BA 19) | — | — | — | — | — | — | — | — | −16 | −62 | 4 | >50 |
| Low > high frequency | ||||||||||||
| Frontal | ||||||||||||
| Inferior frontal gyrus (BA 44) | −40 | 15 | 28 | 4.4 | −42 | 15 | 28 | 4.5 | −40 | 10 | 28 | 6.4 |
| Inferior frontal gyrus (BA 44/45) | −46 | 27 | 17 | 6.4 | −46 | 29 | 21 | 4.2 | −31 | 28 | 11 | 4 |
| 32 | 22 | 8 | 5.6 | — | — | — | — | 33 | 12 | 12 | 4.4 | |
| Anterior cingulate (BA 6) | −4 | 14 | 44 | 3.6 | — | — | — | — | −5 | 17 | 45 | 5.6 |
| — | — | — | — | — | — | — | — | 5 | 12 | 45 | 4.8 | |
Left fusiform activation in the Block (fixation) experiment was not clearly separable from the occipital activation.