Table I.

Signal increases in somatosensory cortex during acupuncture vs. tactile stimulation with identical paradigm (n = 3)

Talairach coordinates			Activated volume (cc)	Tactile stimulation skin over left LI 4 area		Acupuncture left LI 4
R‐L	A‐P	S‐I		Signal change, % mean ± SD	P value max voxel	Signal change, % mean ± SD	P value max voxel
Primary somatosensory cortex
56	−15	50	0.27	0.18 ± 0.12**	2.7 × 10−6	−0.03 ± 0.08	3.0 × 10−2
−59	−18	43	1.12	0.39 ± 0.15***	7.4 × 10−16	0.02 ± 0.12	8.9 × 10−1
Secondary somatosensory cortex
59	−21	21	0.99	0.34 ± 0.14	2.8 × 10−12	0.19 ± 0.10	1.5 × 10−6
−50	−18	18	2.30	0.32 ± 0.14*	3.8 × 10−17	0.11 ± 0.12	9.0 × 10−4

^* P < 0.05

^** P < 0.001

^*** P < 0.0001.