Figure 1.

Areas of significantly greater activation in midline regions during the evaluation of unpleasant compared to matched neutral words. Shown are all significantly activated clusters (defined as a peak P ≤ 0. 0001 within a cluster of five voxels with P ≤ 0.005) across three adjacent sagital slices, centered at X = +3 (R) and X = −3 (L). Activations shown include the anteromedial orbital cortex bilaterally (*) and the left subgenual (black arrow) and caudal posterior cingulate (white arrow) cortices. Activated voxels arer superimposed on a high‐resolution MR image normalized into Talairach space.