Table 1. Statistical analysis for secondary tumorsphere formation assay.
Condition | Fold Change | 95% C.I. | p-value |
---|---|---|---|
SUM149 | |||
DSMO | 1 (reference) | NA | |
GSK461364 | 1.17 | 0.89–1.55 | 0.26 |
Docetaxel | 2.12 | 1.65–2.71 | <0.001 |
GSK461364+Docetaxel | 0.21* | 0.13–0.35 | <0.001 |
*Interaction p-value < 0.001 | |||
SUM159 | |||
DSMO | 1 (reference) | NA | |
GSK461364 | 1.67 | 1.13–2.49 | 0.01 |
Docetaxel | 1.70 | 1.14–2.52 | 0.01 |
GSK461364+Docetaxel | 0.20* | 0.09–0.43 | <0.001 |
*Interaction p-value < 0.001
C.I., confidence intervals; NA, not applicable.