Table 1.

Clinical and biochemical parameters compared between various study groups

Variable	Control (N = 94)	Mild NAFLD (N = 45)	Severe NAFLD (N = 19)	MetS only (N = 74)	NAFLD and MetS combined (N = 40)	Total (N = 272)	p-value
Age (years) (Mean ± SD)	48.7 ± 12.6	44.6 ± 14.4	48.4 ± 14.5	65.6 ± 12.1	56.4 ± 12.4	53.7 ± 15.1	< 0.001
Gender M:F	27:73	42:58	42:58	32:68	52:48	36:64	0.060
BMI (kg/m2) (Mean ± SD)	27.6 ± 5.9	29.9 ± 7.8	30.7 ± 5.9	28.9 ± 6.4	33.9 ± 8.6	29.6 ± 7.1	< 0.001
Waist Circumference (cm) (Mean ± SD)	93.7 ± 13.1	99.4 ± 17.8	101.5 ± 11.9	99 ± 14.1	111.5 ± 20.3	99.3 ± 16.3	< 0.001
Smoker	28	9	1	18	8	64	0.186
Hypertension	0	0	0	64	37	101	< 0.001
Anti-hypertensive medications	0	0	0	62	37	99	< 0.001
Diabetes mellitus	0	0	0	53	33	87	< 0.001
Anti-Diabetic medications	0	0	0	49	33	82	< 0.001
Systolic blood pressure (mm of Hg) (Mean ± SD)	118.1 ± 11.2	123.9 ± 10.7	121.9 ± 33.8	141.2 ± 22.8	131.4 ± 17.2	127.5 ± 20.2	< 0.001
Diastolic blood pressure (mm of Hg) (Mean ± SD)	74.1 ± 8.10	73.5 ± 10.20	76.5 ± 22.1	80.5 ± 14.9	76.9 ± 7.3	76.3 ± 12.1	0.006
Pulse pressure (mm of Hg) (Mean ± SD)	43.9 ± 10.40	50.5 ± 9.0	45.4 ± 17.7	59.9 ± 20.4	54.5 ± 15.3	51.1 ± 16.1	< 0.001
Heart Rate (beats per minute) (Mean ± SD)	75.9 ± 10.1	75.3 ± 10.5	80.9 ± 23.6	84.5 ± 15.9	85.0 ± 12.3	79.8 ± 14.1	< 0.001
Triglyceride level (mg/dL) (Mean ± SD)	91.4 ± 51.3	115.7 ± 79.9	129.2 ± 150.7	165.8 ± 179.3	216.9 ± 122.9	135.9 ± 126.1	< 0.001
ALT (U/L) (Mean ± SD)	16.6 ± 6.1	29.6 ± 27.2	41.4 ± 28.9	23.9 ± 27.0	41.2 ± 27.5	26.1 ± 24.1	< 0.001
AST (U/L) (Mean ± SD)	19.3 ± 5.6	24.8 ± 14.9	48.7 ± 62.2	27.7 ± 25.7	36.4 ± 25.2	27.01 ± 25.3	< 0.001

Abbreviations: BMI: body mass index, AST: aspartate aminotransferase, ALT: alanine aminotransferase.