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. 2019 Nov 15;13:1234. doi: 10.3389/fnins.2019.01234

FIGURE 1.

FIGURE 1

Effect of glucose on stressor-induced S-opsin-labeled cone loss from mixed retinal cell cultures. Representative images from untreated (A), vehicle-treated (C,E,G) or glucose (5 mM)-treated (B,D,F,H) cultures additionally exposed to (C,D), 100 μM tbH (E,F), 500 μM sodium azide (G,H), 1 mM sodium azide. These data are followed by graphs quantifying the positive effect of glucose on tBH-induced (I) and sodium azide-induced (J) cone cell loss. It is evident that both tbH and sodium azide are markedly destructive to S-opsin labeled cones in culture and that glucose has clear protective influences on these cells in both cases. Values represent mean ± SEM, where n = 8 determinations from separate cultures. ∗∗P < 0.01, and ∗P < 0.05 by Student’s paired t-test with Holm-Bonferroni correction. Scale bar, 50 μm.