Table 3.
Parameters | Controls | Cases | ΔT1 − T0 | |||
---|---|---|---|---|---|---|
T0 | T1 | T0 | T1 | Controls | Cases | |
Weight (kg) | 60.9 ± 3.1 | 61.2 ± 3.0 | 82.7 ± 3.4*** | 79.2 ± 3.2*** | 0.4 ± 0.4 | −3.5 ± 1.2§ |
BMI (kg/m2) | 21.6 ± 0.6 | 21.7 ± 0.6 | 30.2 ± 1.0*** | 28.8 ± 0.9***,## | 0.1 ± 0.1 | −1.3 ± 0.4§ |
Total Cholesterol (mg/dl) | 201.8 ± 9.9 | 201.2 ± 14.2 | 195.5 ± 7.6 | 197.6 ± 9.3 | 1.4 ± 5.9 | 2.0 ± 6.2 |
HDL Cholesterol (mg/dl) | 51.0 ± 5.0 | 55.3 ± 5.2 | 58.5 ± 4.0 | 61.6 ± 3.8 | 4.3 ± 3.1 | 3.1 ± 2.2 |
LDL Cholesterol (mg/dl) | 130.3 ± 8.1 | 125.8 ± 10.8 | 117.3 ± 7.4 | 117.8 ± 8.8 | −4.5 ± 4.7 | 0.5 ± 5.0 |
Triglycerides (mg/dl) | 102.5 ± 12.8 | 93.9 ± 7.7 | 98.9 ± 7.4 | 90.9 ± 6.0 | −8.7 ± 17.4 | −8.0 ± 8.2 |
Fasting glucose (mg/dl) | 96.6 ± 3.9 | 92.0 ± 4.9 | 88.7 ± 1.9 | 91.0 ± 2.0 | −4.7 ± 3.3 | 2.2 ± 1.4§ |
Insulin (µU/ml) | 22.9 ± 2.3 | 21.7 ± 1.8 | 29.0 ± 1.4* | 26.9 ± 1.4# | −1.2 ± 0.9 | −2.1 ± 0.5 |
C-peptide (ng/ml) | 1.7 ± 0.1 | 1.6 ± 0.1 | 2.2 ± 0.1** | 1.8 ± 0.1 | −0.2 ± 0.03 | −0.4 ± 0.1 |
*P < 0.05, **P < 0.01 and ***P < 0.001 vs control group at same time point (ex. Control T0 x Case T0 ).
#P < 0.05, ##P < 0.01 and ### P <0.001 vs T0 in the same group (ex. Control T0 x Control T1 ).
Both Two-Way ANOVA and Bonferroni’s MCT.
§P < 0.05 vs controls. Unpaired t-test.