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. 2019 Nov 15;9:1224. doi: 10.3389/fonc.2019.01224

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Copyright © 2019 Buszek and Chung.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Median OS ranges from observational studies meeting inclusion criteria for the most common histologies of LMD. OS, overall survival; LMD, leptomeningeal disease. *Excluding trial by Roldan et al. (73) which included only patients with oligodendrogliomas and reported an OS of 32 months.