Table 7.

Leukemia/Lymphoma: included studies evaluating the use of RT for LMD.

References	Study type	Study Pop with LMD (n)	Treatment era (years)	Median age, years	Treatment	Median OS (months)	Conclusions
Currie et al. (74)	Obs	3	1988	63	100% FBRT	NR	RT leads to considerable clinical improvement
Milgrom et al. (75)	Obs	44	2006–2016	NR	95% WBRT; 2% CSI; 70% C	7	RT has high response rates

RT, radiotherapy; LMD, leptomeningeal disease; Pop, population; Obs, observational study; PP, practice patterns; NR, not reported; BSC, best supportive care; C, chemotherapy alone; ITC, intrathecal chemotherapy; WBRT, whole brain radiotherapy; FSRT, spine RT; CSI, craniospinal RT.