Table 9.

Esthesioneuroblastoma: included studies evaluating the use of RT for LMD.

Reference	Study type	Study Pop with LMD (n)	Treatment era (years)	Median age, years	Treatment	Median OS (months)	Conclusions
Chamberlain et al. (78)	Obs	4	2002	53	50% FSRT; 50% WBRT + ITC	NR	Treatment has acceptable toxicity and reasonable disease palliation

RT, radiotherapy; LMD, leptomeningeal disease; Pop, population; Obs, observational study; PP, practice patterns; NR, not reported; BSC, best supportive care; C, chemotherapy alone; ITC, intrathecal chemotherapy; WBRT, whole brain radiotherapy; FSRT, spine RT; CSI, craniospinal RT.