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. 2019 Nov 21;9:17283. doi: 10.1038/s41598-019-53471-0

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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GSEA. (a–c) Displays the top 3 most upregulated gene sets of GSEA based on the hallmark gene sets. (d–h) shows the top 5 most upregulated gene sets of GSEA based on the GO gene sets. The enrichment score (NES), false discovery rate (FDR) and the normalized enrichment score are shown for each gene set. The bars at the bottom of the panels are the corresponding genes of certain gene sets. (i) Displays the relative location of genes in the ranked list.