Skip to main content
. 2019;10(5-6):119–133. doi: 10.18632/genesandcancer.197

Figure 3. HDAC8 binds to ADRM1 through the PRU domain.

Figure 3

A. Extracts from U87 cells treated with TMZ for 48 hours were immunoprecipitated with a FLAG antibody and subject to Coomassie blue staining. B. HA immunoprecipitation of extracts from U87 and T98G cells expressing FLAG-HDAC8 and HA-ADRM1 and treated with TMZ for 48 hours. C. Schematics of the different FLAG-ADRM1 constructs used in D. D. FLAG immunoprecipitation of extracts from HeLa cells transfected with different constructs of FLAG-ADRM1 and HA-HDAC8. E. FLAG immunoprecipitation of extracts from HeLa cells transfected with HA-UCH37, myc-HDAC8 and FLAG-ADRM1. F. HA immunoprecipitation of extracts from T98G cells expressing HA-ADRM1 and FLAG-HDAC8.