A. OncoPrint representing alteration of TNC in TCGA dataset with prostate adenocarcinoma cases (Total N = 499, N = 498 sequenced patient samples). Genetic alterations are color coded: Amplification, red; Gain of function, pink; Missense mutations, green; deep deletion, blue; No alterations, grey. Patient characteristics (color coded separately for each of the characteristics) including Cancer type, Radical prostatectomy Gleason score, Race category and PSA are represented in horizontal rows. B. Diagnostic Gleason score in patients with specifically TNC alteration. C. Graph showing stratification of TNC altered tumor samples under different Gleason score category. Each bar of the graph represents a class of Gleason score and stratified for the alteration in TNC.