Table 4.

Univariate and multivariate Cox analysis in TCGA LrGG cohort.

	Univariate analysis		Multivariate analysis
	HR (95% CI)	P value (Wald test)	HR (95% CI)	P value (Wald test)
MGMT promoter	2.981	<0.001	1.010	0.970
(Unemethylated vs. Methylated)	(2.033-4.370)		(0.610-1.671)
IDH status	9.243	<0.001	3.368	0.001
(Wt vs. Mutant)	(6.261-13.650)		(1.607-7.059)
Gender	1.093	0.625	–	–
(Male vs Female)	(0.766-1.559)		–	–
Age	0.359	<0.001	0.531	0.003
(≤45 vs >45)	(0.248-0.519)		(0.352-0.802)
WHO grade	0.300	<0.001	0.448	<0.001
(GII vs. GIII)	(0.203-0.443)		(0.288-0.699)
Risk Score	0.187	<0.001	0.490	0.026
(Low vs. High)	(0.131-0.268)		(0.261-0.920)