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. 2019 Nov 13;13(1):17–24. doi: 10.1016/j.tranon.2019.09.003

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© 2019 The Authors

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

TILs expressing CD39 and PD-1 and relapse of NSCLC. (A) Fractions of tumor-infiltrating CD4⁺ T cells coexpressing CD39 and PD1 correlated significantly with clinical stage in patients with NSCLC. A trend towards correlation was found in fractions of tumor-infiltrating CD8⁺ T cells coexpressing CD39 and PD1. (B) Spearman's rank correlation test was used to determine correlation. TILs: Tumor-infiltrating lymphocytes. Patients with relapse of NSCLC within the first 12 months after surgery are displayed in red points.