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TNF-α Reduces NO Bioavailability in CMECs
(A and B) NO levels in CMEC. Acetylcholine (Ach)−induced upregulation of NO production in CMECs. Similar to L-NAME treatment, TNF-α reduced CMEC NO levels. (n = 4 to 50, refers to number of cells per group from 3 independent experiments). Data represented as mean ± SD. Other abbreviations as in Figures 1, 2, and 3.
