Table 4.
Change in clinical scores at the baseline and the first follow-up MRI in the groups of excellent outcome and good outcome.
| Excellent (n = 43) | Good (n = 11) | P value* | |||
|---|---|---|---|---|---|
| At baseline | At 1st MRI | At baseline | At 1st MRI | ||
| mRS | 2.57 ± 0.67 | 1.84 ± 0.69 | 2.82 ± 0.98 | 2.55 ± 0.82 | 0.012 |
| ∆mRS | 0.72 ± 0.55 | 0.27 ± 0.47 | 0.026 | ||
| iNPHGS total | 6.36 ± 1.96 | 4.28 ± 1.92 | 6.36 ± 2.50 | 5.45 ± 2.81 | 0.118 |
| ∆total | 2.07 ± 1.47 | 0.91 ± 1.45 | 0.007 | ||
| gait | 2.52 ± 0.51 | 1.56 ± 0.59 | 2.45 ± 0.69 | 2.09 ± 0.94 | 0.024 |
| ∆gait | 0.98 ± 0.46 | 0.36 ± 0.67 | <0.001 | ||
| cognitive | 1.83 ± 0.88 | 1.44 ± 0.80 | 2.00 ± 0.89 | 1.73 ± 0.90 | 0.255 |
| ∆cognitive | 0.37 ± 0.62 | 0.27 ± 0.47 | 0.743 | ||
| urinary | 2.00 ± 0.96 | 1.28 ± 0.85 | 1.91 ± 1.30 | 1.64 ± 1.21 | 0.387 |
| ∆urinary | 0.72 ± 0.77 | 0.27 ± 0.47 | 0.060 | ||
| TUG | 26.2 ± 30.4 | 13.5 ± 10.0 | 32.9 ± 33.7 | 16.7 ± 7.67 | 0.058 |
| ∆TUG | 12.7 ± 29.4 | 16.4 ± 27.0 | 0.761 | ||
| 10 M Walk | 18.4 ± 17.3 | 10.2 ± 15.5 | 19.7 ± 20.9 | 12.2 ± 6.72 | 0.195 |
| ∆10 M Walk | 8.2 ± 15.8 | 7.6 ± 21.3 | 0.232 | ||
| MMSE | 21.6 ± 5.6 | 23.6 ± 5.0 | 21.5 ± 6.7 | 23.1 ± 5.1 | 0.777 |
| ∆MMSE | 1.7 ± 4.5 | 2.2 ± 2.6 | 0.986 | ||
| FAB | 9.58 ± 2.9 | 11.4 ± 3.1 | 10.0 ± 4.1 | 10.5 ± 3.5 | 0.573 |
| ∆FAB | 1.7 ± 2.8 | 0.7 ± 3.2 | 0.240 | ||
Data are presented as the mean ± standard deviation unless otherwise noted.
∆ indicates the difference between score at the baseline and that at the first follow-up MRI.
*Probability value of the Wilcoxon rank-sum test: comparison between excellent and good outcomes
mRS, modified Rankin Scale; iNPHGS, idiopathic normal pressure hydrocephalus grading scale; TUG, timed 3-m up-and-go test; 10 M Walk, 10-m straight walking test; MMSE, mini-mental state examination; FAB, frontal assessment battery.