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. 2019 Nov 19;26:100434. doi: 10.1016/j.ijcha.2019.100434

Table 1.

Clinical characteristics of all patients with and without obstructive CAD.

All N = 150 No obstructive CAD N = 63 Obstructive CAD N = 87 P value*
Demographics
 Age in years 67.6 (11.5) 66 (10.39) 68 (12.23) 0.470
 Male sex 96 (64%) 29 (48%) 67 (74%) 0.001
 BMI 28.1 (5.4) 28.7 (6.3) 26.9 (4.6) 0.291



Medical history
 History of CVD 111 (74%) 41 (68%) 70 (78%) 0.196
 History of CAD 25 (17%) 3 (5%) 22 (24%) 0.002
 History of MI 18 (12%) 2 (3%) 16 (18%) 0.008
 History of PAD 10 (7%) 3 (5%) 7 (8%) 0.504
 Diabetes mellitus 35 (23%) 14 (23%) 21 (23%) 0.575
 Hypertension 97 (65%) 36 (60%) 61 (68%) 0.329
 Dyslipidemia 87 (58%) 37 (62%) 50 (56%) 0.458
 Current smoker 39 (26%) 15 (25%) 24 (27%) 0.820
 Family history of CAD 45 (30%) 19 (32%) 26 (30%) 0.783



Medication
 Platelet aggregation inhibitors† 85 (57%) 29 (48%) 56 (62%) 0.093
 Anticoagulants 30 (20%) 11 (18%) 19 (21%) 0.667
 Beta-blockers 81 (54%) 31 (52%) 50 (56%) 0.640
 Statins 87 (58%) 37 (62%) 50 (56%) 0.458
 ACE inhibitor or ARB 57 (38%) 19 (32%) 38 (42%) 0.192
 Calcium channel blockers 34 (23%) 16 (27%) 18 (20%) 0.339
 Loopdiuretics 22 (15%) 9 (15%) 13 (14%) 0.925
 Nitroglycerin 57 (38%) 22 (37%) 35 (39%) 0.784



82Rb PET-CT findings
 Rest LVEF 58 (16) 61 (17) 57 (16) 0.670
 Stress LVEF 61 (17) 61 (17) 69 (16) 0.947
 SDS 4 (5) 1 (2) 6 (4) <0.001
 RPP 11,024 (3068) 10,341 (2258) 11,501 (3458) 0.227
 Rest MBF uncorrected 1.15 (0.38) 1.12 (0.33) 1.17 (0.42) 0.511
 Rest MBF corrected 0.86 (0.25) 0.89 (0.24) 0.83 (0.25) 0.170
 Stress MBF 2.41 (1.88) 2.61 (0.77) 2.28 (2.35) 0.313
 CFR 3.19 (0.99) 3 (1) 3 (1) 0.584



CAC results
 0 8 (5%) 5 (8%) 3 (3%) 0.038
 1–100 27 (18%) 17 (27%) 10 (12%) 0.007
 101–300 26 (17%) 14 (22%) 12 (14%) 0.043
 >300 89 (59%) 27 (43%) 62 (71%) <0.001

Continuous variables are presented as mean (SD), categorical variables as n(%). * P value for comparison between groups with and without obstructive CAD. CVD = cardiovascular disease, CAD = coronary artery disease, MI = myocardial infarction, PAD = peripheral artery disease. †Aspirin, clopidogrel or ticagrelor, LVEF = Left ventricular ejection fraction. SDS = Summed Difference Score [15], RPP = rate pressure product, MBF = myocardial bloodflow, CFR = Coronary flow reserve, CAC = Coronary Artery Calcium.